Early hyperostosis frontalis interna found incidentally by NaF18 PET/CT bone scan

Abstract

The patient is an 80 year old white male who was referred for NaF18 PET/CT bone scan to evaluate for possible prostate cancer metastasis. We found no evidence of prostate cancer metastasis but there was an incidental finding of early hyperostosis frontalis interna in bilateral inner tables of frontal bone on PET/CT scan. The thickness of the inner table of frontle bones was normal on CT scan images; however, increased osteoplastic activity consistent with early active hyperostosis frontalis interna was seen on NaF18 PET/CT images. The patient had no neuropsychological symptoms. To our knowledge, this is the first reported case of early hyperostosis frontalis interna found incidentally by NaF18 PET/CT.