Laryngotracheal giant cell tumor: case report and literature review

Abstract

Giant cell tumor is a benign but locally aggressive tumor typically found in the long bones but has also been reported in several head and neck locations. Although rare, it can arise from endochondral bone within the larynx, however there have been no prior reported occurrences in the trachea. We report a giant cell tumor of the cricoid cartilage presenting as an endotracheal mass with dysphonia and dyspnea on exertion which was treated with endoscopic excision. The tumor is diagnosed histologically as no clinical or radiographic findings are specific for giant cell tumor. Optimal treatment and recurrence rate is unknown but review of laryngeal lesions suggests complete excision has favorable results. Radiation therapy poses risk for malignant transformation.