Chondroblastoma-like chondroma of soft tissue: A report of two cases

Abstract

Soft tissue chondroma is a benign cartilaginous neoplasm composed of cells with a chondroid phenotype. Chondromas of soft tissue can have variable histological appearances including deposition of calcium, histiocytic reaction, ossification, and myxoid change. One notable variation is the presence of histological features reminiscent of chondroblastoma of the bone, and the term used in this scenario is chondroblastoma-like chondroma of soft tissue. There have been fourteen previous case reports of chondroblastoma-like chondroma of soft tissue, predominantly in the hands; with one case being reported in the base of the skull. We report two cases of chondroblastoma-like chondroma of soft tissue occurring in the hand and foot. To the best of our knowledge this is the first reported case of chondroblastoma-like chondroma of soft tissue in the foot.